gene 759 words KG: ent-gene-47202345
Contents

ARC Gene

🧬 Gene Info
Gene SymbolARC
Full NameActivity-Regulated Cytoskeleton-Associated Protein
Chromosome8q24.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressioncortex and hippocampus with synaptic localization
PathwaysAkt, Complement, Endocytosis, Exocytosis, Long-Term Potentiation
UniProt IDQ7Z594
NCBI Gene ID23237
Ensembl IDENSG00000132740
OMIM602473
GeneCardsARC
Human Protein AtlasARC
Associated DiseasesAls, Alzheimer, Glaucoma, Macular Degeneration, Retinopathy
InteractionsActin, AGING, AIF1, Akt, AKT, ALZHEIMER
SciDEX HypothesesSynaptic Activity-Dependent Protection System
KG Connections245 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (21)

Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
← Prevpg 2/2

Related Analyses (7)

Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (15)

Alzheimer Indonesia
institution · KG edge: inhibits
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: therapeutic_target
Apoptosis in Neurodegeneration
entity · KG edge: activates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
AgRP (Agouti-Related Protein) Neurons
cell · KG edge: produces

Knowledge Graph (4 edges)

h-9ff41c2036 targets ent-gene-47202345
ent-gene-47202345 targeted_by h-9ff41c2036
ent-gene-47202345 data_in benchmark_ot_ad_answer_key:ARC
benchmark_ot_ad_answer_key:ARC data_in ent-gene-47202345

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