disease

Retinopathy

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Retinopathy: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

241Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

Disease Info

Associated Genes	INFLAMMATION, CYTOKINES, DIABETIC RETINOPATHY, ARC, DIABETES MELLITUS, VEGF, NEURODEGENERATION, ANXIETY
KG Connections	236 knowledge graph edges
Databases	OMIM Orphanet ClinicalTrials PubMed

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Retinopathy["Retinopathy"] -->|"therapeutic target"| Als["Als"]
    Retinopathy["Retinopathy"] -->|"therapeutic target"| Inflammation["Inflammation"]
    Retinopathy["Retinopathy"] -->|"associated"| Diabetes["Diabetes"]
    Retinopathy["Retinopathy"] -->|"therapeutic target"| Oxidative_Stress["Oxidative Stress"]
    Retinopathy["Retinopathy"] -->|"associated"| Glaucoma["Glaucoma"]
    Retinopathy["Retinopathy"] -->|"causes"| Diabetes_1["Diabetes"]
    DIABETIC_RETINOPATHY["DIABETIC RETINOPATHY"] -->|"therapeutic target"| Retinopathy["Retinopathy"]
    INFLAMMATION["INFLAMMATION"] -->|"therapeutic target"| Retinopathy["Retinopathy"]
    DIABETIC_RETINOPATHY_2["DIABETIC RETINOPATHY"] -->|"associated"| Retinopathy["Retinopathy"]
    DIABETES_MELLITUS["DIABETES MELLITUS"] -->|"causes"| Retinopathy["Retinopathy"]
    style Retinopathy fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (84)

Target	Relation	Type	Str
Als	therapeutic_target	disease	0.75
Inflammation	therapeutic_target	disease	0.75
Diabetes	associated_with	disease	0.75
Oxidative Stress	therapeutic_target	pathway	0.70
Glaucoma	associated_with	disease	0.65
Diabetes	causes	disease	0.65
Diabetes	activates	disease	0.65
Immune Response	associated_with	pathway	0.60
Oxidative Stress	contributes_to	pathway	0.60
Autophagy	therapeutic_target	pathway	0.60
Apoptosis	therapeutic_target	pathway	0.60
Senescence	therapeutic_target	pathway	0.60
Mitochondrial Function	therapeutic_target	pathway	0.60
Epigenetic	therapeutic_target	pathway	0.60
Epigenetic	causes	pathway	0.60
Ferroptosis	activates	pathway	0.60
Ferroptosis	associated_with	pathway	0.60
Cholesterol	therapeutic_target	pathway	0.60
Differentiation	associated_with	pathway	0.60
Angiogenesis	therapeutic_target	pathway	0.60
Stem Cell	treats	pathway	0.60
Pi3K/Akt	associated_with	pathway	0.60
Angiogenesis	interacts_with	pathway	0.60
Senescence	interacts_with	pathway	0.60
Apoptosis	activates	pathway	0.60
Tgf-Β	inhibits	pathway	0.60
Fibrosis	associated_with	disease	0.55
Inflammation	associated_with	disease	0.55
Als	protects_against	disease	0.55
Neurodegeneration	protects_against	disease	0.55
Diabetes	contributes_to	disease	0.55
Als	implicated_in	disease	0.55
Neurodegeneration	causes	disease	0.55
Depression	associated_with	disease	0.55
Anxiety	associated_with	disease	0.55
Atherosclerosis	activates	disease	0.55
Diabetes	therapeutic_target	disease	0.55
Nephropathy	associated_with	disease	0.55
Als	associated_with	disease	0.55
Ischemia	treats	disease	0.55
Ischemia	biomarker_for	disease	0.55
Diabetes	biomarker_for	disease	0.55
Als	interacts_with	disease	0.55
Aging	interacts_with	disease	0.55
Als	activates	disease	0.55
Hepatitis	inhibits	disease	0.55
Inflammation	inhibits	disease	0.55
Oxidative Stress	associated_with	pathway	0.55
Blood-Brain Barrier	activates	pathway	0.55
Autophagy	associated_with	pathway	0.55

Incoming (157)

Source	Relation	Type	Str
DIABETIC RETINOPATHY	therapeutic_target	gene	1.00
INFLAMMATION	therapeutic_target	gene	0.85
DIABETIC RETINOPATHY	associated_with	gene	0.85
DIABETES MELLITUS	causes	gene	0.85
OXIDATIVE STRESS	therapeutic_target	gene	0.75
DIABETIC RETINOPATHY	causes	gene	0.75
DIABETES MELLITUS	therapeutic_target	gene	0.75
DIABETIC RETINOPATHY	activates	gene	0.75
INFLAMMATION	associated_with	gene	0.65
CYTOKINES	associated_with	gene	0.65
VEGF	protects_against	gene	0.65
NEURODEGENERATION	protects_against	gene	0.65
OXIDATIVE STRESS	contributes_to	gene	0.65
DIABETIC RETINOPATHY	contributes_to	gene	0.65
NAD	therapeutic_target	gene	0.65
APOPTOSIS	therapeutic_target	gene	0.65
SIRT1	therapeutic_target	gene	0.65
AUTOPHAGY	therapeutic_target	gene	0.65
ARC	associated_with	gene	0.65
MITOCHONDRIAL DYSFUNCTION	therapeutic_target	gene	0.65
DNA	therapeutic_target	gene	0.65
MITOCHONDRIA	therapeutic_target	gene	0.65
CYTOKINES	interacts_with	gene	0.65
VEGF	causes	gene	0.65
NEURODEGENERATION	causes	gene	0.65
ANXIETY	associated_with	gene	0.65
DEPRESSION	associated_with	gene	0.65
PARKINSON	biomarker_for	gene	0.65
PARKINSON'S DISEASE	biomarker_for	gene	0.65
FERROPTOSIS	activates	gene	0.65
DIABETES MELLITUS	associated_with	gene	0.65
FERROPTOSIS	associated_with	gene	0.65
HBA1	therapeutic_target	gene	0.65
Diabetes	therapeutic_target	disease	0.65
NEUROINFLAMMATION	therapeutic_target	gene	0.65
VEGF	therapeutic_target	gene	0.65
DNA	treats	gene	0.65
DIABETIC RETINOPATHY	biomarker_for	gene	0.65
PI3K	associated_with	gene	0.65
FN1	interacts_with	gene	0.65
GENES	interacts_with	gene	0.65
AKT	associated_with	gene	0.65
RAGE	associated_with	gene	0.65
C-JUN	activates	gene	0.65
APOPTOSIS	activates	gene	0.65
FOS	activates	gene	0.65
SIRT1	activates	gene	0.65
C-FOS	activates	gene	0.65
JUN	activates	gene	0.65
INFLAMMATION	inhibits	gene	0.65

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Retinopathy

Understanding Entity Pages

Wiki Pages (20)

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