| Gene Symbol | BCL2A1 |
| Chromosome | 15q24.2 |
| Protein Family | BCL2 family (anti-apoptotic) |
| Function | BCL2A1 encodes an anti-apoptotic protein that regulates the intrinsic (mitochondrial) apoptosis pathway: |
| Primary Expression | hematopoietic cells but is also induced in neurons under stress conditions[@bcla2010] |
| Amino Acids | 175 aa |
| UniProt ID | Q9GZW8 |
| NCBI Gene ID | 602 |
| GeneCards | BCL2A1 |
| Human Protein Atlas | BCL2A1 |
| Alternative Names | BFL-1, A1, GRS |
| Cell Type | Expression Level |
| Neurons | Low (inducible) |
| [Microglia](/cell-types/microglia-neuroinflammation) | Moderate |
| [Astrocytes](/entities/astrocytes) | Low-Moderate |
| Associated Diseases | neurodegeneration |
| Interactions | XIAP, BCL2, RBM10, CASP3, CASP6, CEBPB |
| KG Connections | 17 knowledge graph edges |
| Databases | GeneCardsHPASTRING |