gene 567 words KG: CEBPB 2026-03-24
kind:genesection:genesstate:published
Contents

CEBPB Gene

🧬 Gene Info
Gene SymbolCEBPB
Protein TypeTranscription Factor
FunctionThey function as homo- or heterodimers and regulate gene expression through their leucine zipper DNA-binding domains.
Primary Expressionvarious tissues including brain, where it plays important roles in:
PathwaysInnate Immunity
UniProt IDP17676
Ensembl IDENSG00000172216
GeneCardsCEBPB
Human Protein AtlasCEBPB
Associated DiseasesAls, Cancer, Carcinoma, Cirrhosis
InteractionsAKT, EGF, EGFR, ERCC3, PDK1, PI3K
KG Connections212 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (11)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.63
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (6)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (13)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: therapeutic_target
Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: activates
CCL20 Gene
gene · KG edge: activates
BNIP3L — BCL2 Interacting Protein 3 Like (NIX)
gene · KG edge: inhibits

Knowledge Graph (12 edges)

CEBPB activates AKT
CEBPB associated_with CYP3A4
CEBPB activates EGF
CEBPB activates EGFR
CEBPB activates ERCC3
CEBPB associated_with MTOR
CEBPB activates PDK1
CEBPB activates PI3K
CEBPB activates MAP1LC3B
CEBPB inhibits SPG7