| Gene Symbol | CPLX2 |
| Full Name | Complexin 2 |
| Chromosome | 5q31.2 |
| Function | Complexin 2 is a cytosolic protein that regulates SNARE complex assembly |
| Amino Acids | 150 aa |
| UniProt ID | O75178 |
| NCBI Gene ID | 10857 |
| Ensembl ID | ENSG00000128487 |
| OMIM | 605738 |
| GeneCards | CPLX2 |
| Human Protein Atlas | CPLX2 |
| Disease | Mechanism |
| [Alzheimer's Disease](/diseases/alzheimers-disease) | CPLX2 levels reduced in AD hippocampus; involved in synaptic dysfunction |
| [Parkinson's Disease](/diseases/parkinsons-disease) | Altered SNARE regulation affects dopaminergic transmission |
| Epilepsy | Mutations affect release probability and seizure threshold |
| Associated Diseases | Alzheimer, neurodegeneration |
| Interactions | DNM1L, ICAM1, PINK1, TFAM, TNF, BDNF |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsHPASTRING |