| Gene Symbol | CTSS |
| Full Name | Cathepsin S |
| Chromosome | 1q21.3 |
| Protein Family | Papain family cysteine proteases |
| Protein Type | Protease |
| Function | encodes a lysosomal cysteine protease that has emerged as a critical player in both immune function and neurodegenerative disease pathogenesis. |
| Primary Expression | Microglia, Macrophages, Dendritic cells |
| Molecular Weight | 37 kDa |
| Amino Acids | 331 aa |
| UniProt ID | P25774 |
| NCBI Gene ID | 1520 |
| Ensembl ID | ENSG00000163131 |
| OMIM | 600565 |
| GeneCards | CTSS |
| Human Protein Atlas | CTSS |
| Associated Diseases | Aging |
| Interactions | AHR, CTSD, LAMP2, JAK2, STAT3, APP |
| KG Connections | 60 knowledge graph edges |
| Databases | GeneCardsHPASTRING |