| Gene Symbol | DARS2 |
| Chromosome | 12q24.1 |
| Protein Type | Synthetase |
| Function | is a critical mitochondrial aminoacyl-tRNA synthetase that plays an essential role in mitochondrial protein synthesis. |
| Subcellular Localization | mitochondria: |
| Molecular Weight | 73.8 kDa |
| Amino Acids | 50 aa |
| Pathways | Invasion, Metastasis |
| Ensembl ID | ENSG00000117682 |
| GeneCards | DARS2 |
| Human Protein Atlas | DARS2 |
| Aminoacylation | Attaches Asp to tRNA^Asp in mitochondria |
| ATP-dependent | Uses ATP to form aminoacyl-tRNA |
| Dimer formation | Functional as homodimer |
| Import | Contains mitochondrial targeting sequence |
| Associated Diseases | neurodegeneration |
| Interactions | CDK4, ERK, MYC, PINK1 |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!