gene 836 words KG: DNAJC2 2026-03-24
kind:genesection:genesstate:published
Contents

DNAJC2 - DnaJ Heat Shock Protein Family Member C2

🧬 Gene Info
Gene SymbolDNAJC2
Full NameDnaJ Heat Shock Protein Family Member C2
AliasesPage for DNAJC2, Page for DNAJC2 Protein
Chromosome9p24.
Protein TypeChaperone
FunctionIn neurons, DNAJC2 participates in
Primary Expressionvarious brain regions:
Molecular Weight66.3 kDa
Amino Acids640 aa
PathwaysApoptosis, Complement, Exocytosis, Mitochondrial Function
UniProt ID[Q9Y2H5](https://www.uniprot.org/uniprot/Q9Y2H5)
Ensembl IDENSG00000137770
GeneCardsDNAJC2
Human Protein AtlasDNAJC2
Associated Diseasesneurodegeneration
KG Connections29 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.48

Related Analyses (6)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (14)

Packard Center for ALS Research
institution · KG edge: regulates
Dementia Australia
institution · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: regulates
PDE4C — Phosphodiesterase 4C
gene · KG edge: regulates
NOX1 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

DNAJC2 regulates CHMP3
DNAJC2 regulates PDE4C
DNAJC2 associated_with BAG1
DNAJC2 regulates VTI1B
DNAJC2 regulates EIF4G1
DNAJC2 regulates NOX1
DNAJC2 regulates NGF
DNAJC2 associated_with DISC1
DNAJC2 associated_with GALNT3
DNAJC2 regulates IREB2