Contents

SGK3 - Serum/Glucocorticoid Regulated Kinase 3

🧬 Gene Info

Gene Symbol	SGK3
Full Name	Serum/Glucocorticoid Regulated Kinase 3
Chromosome	8q12.3
Protein Type	Kinase
Function	The kinase is activated by PDK1-mediated phosphorylation at Thr320, a site conserved across SGK family members [4].
Subcellular Localization	distinguishes SGK3 from other SGK family members and is particularly relevant to [neurodegenerative disease mechanisms](
Amino Acids	644 aa
Exons	14
Pathways	PI3K, mTOR pathway, pi3k, mTOR
Ensembl ID	ENSG00000115297
GeneCards	SGK3
Human Protein Atlas	SGK3
NDRG2	A differentiation-related protein involved in neurite outgrowth
FOXO transcription factors	Regulates neuronal survival and stress responses
Tau protein	SGK3 can phosphorylate tau at multiple sites relevant to Alzheimer's disease pathology [5]
Associated Diseases	neurodegeneration
KG Connections	29 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Knowledge Graph