gene 648 words KG: BAG1 2026-03-22
kind:genesection:genesstate:published
Contents

BAG1 Gene

🧬 Gene Info
Gene SymbolBAG1
Full NameBCL2-Associated Athanogene 1
Chromosome9p12
Protein TypeChaperone
FunctionBAG1 is a co-chaperone that modulates Hsp70/Hsc70 function
Primary Expressionvarious cancers
Molecular Weight46 kDa
Amino Acids110 aa
PathwaysMAPK
UniProt IDO95351
NCBI Gene ID573
GeneCardsBAG1
Human Protein AtlasBAG1
Protein ClassBAG Family Co-chaperones
Associated Diseasesneurodegeneration
InteractionsSOD1, DNAJB6, HSP70, HSPA1A, HSPA8, HSPBP1
KG Connections48 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.48
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor
Score: 0.42

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (13)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: inhibits
Packard Center for ALS Research
institution · KG edge: expressed_in
Dementia Australia
institution · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: regulates
KIF3B — Kinesin Family Member 3B
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

BAG1 inhibits SOD1
BAG1 expressed_in KIF3B
BAG1 regulates VTI1B
BAG1 regulates EIF4G1
BAG1 regulates NOX1
BAG1 regulates NGF
BAG1 associated_with DISC1
BAG1 associated_with GALNT3
BAG1 regulates IREB2
BAG1 interacts_with DNAJB6