gene 1,644 words KG: GALNT3 2026-03-25
kind:genesection:genesstate:publishedtopic:alzheimers
Contents

GALNT3 — Polypeptide N-acetylgalactosaminyltransferase 3

🧬 Gene Info
Gene SymbolGALNT3
Full NamePolypeptide N-acetylgalactosaminyltransferase 3
Functionis a type II transmembrane protein localized to the Golgi apparatus, consistent with other members of the GALNT family.
Primary Expressionvarious tissues including brain, kidney, and pituitary
Subcellular Localizationthe Golgi apparatus, consistent with other members of the GALNT family. The protein consists of several distinct domains
Amino Acids10 aa
PathwaysApoptosis, Complement, Exocytosis, Mitochondrial Function
GeneCardsGALNT3
Human Protein AtlasGALNT3
TissueExpression Level
KidneyHigh
BoneModerate
BrainLow-Moderate
PituitaryModerate
Salivary glandModerate
Associated DiseasesAlzheimer's disease
InteractionsAGO2, Rb, APOPTOSIS, Ras, MIRNAS, AMPK
KG Connections60 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (1)

TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (14)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: inhibits
Packard Center for ALS Research
institution · KG edge: expressed_in
Alzheimer Indonesia
institution · KG edge: regulates
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: activates
EIF4G1 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

GALNT3 regulates IREB2
GALNT3 expressed_in cancer
GALNT3 expressed_in ST6GAL1
GALNT3 expressed_in ST3GAL2
GALNT3 expressed_in Rb
GALNT3 inhibits AGO2
GALNT3 inhibits Rb
GALNT3 regulates COMPLEMENT
GALNT3 regulates Dementia
GALNT3 regulates Schizophrenia