gene 699 words KG: FAN1 2026-03-21
kind:genesection:genesstate:published
Contents

FAN1 Gene

🧬 Gene Info
Gene SymbolFAN1
Full NameFANCD2 Associated Nuclease 1
Chromosome15q13.1-q13.3
Functionis a DNA repair nuclease that plays a critical role in interstrand crosslink repair
Primary Expressionperipheral tissues
Molecular Weight86 kDa
UniProt IDQ8IY92 (FAN1)
NCBI Gene ID22919
Ensembl IDENSG00000101391
OMIM613375
GeneCardsFAN1
Human Protein AtlasFAN1
ApproachRationale
Gene therapyRestore FAN1 function
Small molecule enhancersBoost nuclease activity
Associated DiseasesAls, Huntington, Ms
InteractionsHTT, MSH3, PMS2, DNA
KG Connections15 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph