| Gene Symbol | FLT1 |
| Full Name | Fms Related Receptor Tyrosine Kinase 1 (VEGF Receptor 1) |
| Aliases | VEGF Receptor 1 |
| Chromosome | 13q12.3 |
| Protein Type | Receptor |
| Function | The first three Ig domains are sufficient for VEGF binding, while domains 2-3 are critical for high-affinity interactions. |
| Molecular Weight | 180 kDa |
| Pathways | Angiogenesis, Erk Signaling, Mapk, epigenetic regulation, oxidative stress response |
| UniProt ID | P17948 |
| NCBI Gene ID | 2321 |
| Ensembl ID | ENSG00000102755 |
| OMIM | 165040 |
| GeneCards | FLT1 |
| Human Protein Atlas | FLT1 |
| Associated Diseases | neurodegeneration |
| Interactions | HSPA8, IL1B, TAU, INFLAMMATION, ERK, MICROGLIA |
| KG Connections | 81 knowledge graph edges |
| Databases | GeneCardsHPASTRING |