gene 913 words KG: GATA1 2026-03-21
kind:genesection:genesstate:published
Contents

GATA1 - GATA Binding Protein 1

🧬 Gene Info
Gene SymbolGATA1
Full NameGATA Binding Protein 1
AliasesPage for GATA1
FunctionGATA1 belongs to the GATA family of transcription factors characterized by conserved zinc finger domains that bind the DNA sequence (A/T)GATA(A/G).
PathwaysApoptosis, Cell Cycle
Ensembl IDENSG00000102145
GeneCardsGATA1
Human Protein AtlasGATA1
Associated Diseasesneurodegeneration
InteractionsHSP70, MYC, CREBBP, IL6ST, NR3C1, LRP1
KG Connections30 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

Blood-Brain Barrier SPM Shuttle System
Score: 0.55
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
LRP1-Dependent Tau Uptake Disruption
Score: 0.44
Extracellular Matrix Stiffness Modulation
Score: 0.43

Related Analyses (7)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed

See Also (11)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: interacts_with
LRP1-Enhanced Perivascular Drainage Therapy
idea · KG edge: interacts_with
HSP70 Inducer Therapies for Neurodegeneration
idea · KG edge: activates
SNCA — Alpha-Synuclein
gene · KG edge: contributes_to
MYC Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

GATA1 activates HSP70
GATA1 interacts_with MYC
GATA1 interacts_with CREBBP
GATA1 interacts_with IL6ST
GATA1 interacts_with NR3C1
GATA1 interacts_with LRP1
GATA1 co_expressed_with GATA2
GATA1 activates GATA2
GATA1 activates ST3GAL2
GATA1 activates ST8SIA1