gene 590 words KG: KCNK5 2026-03-22
kind:genesection:genesstate:published
Contents

KCNK5 Gene

🧬 Gene Info
Gene SymbolKCNK5
AliasesTASK-2
Functionis a recognized contributor to progressive synaptic injury and circuit failure in AD/PD/ALS spectra.
Molecular Weight51 kDa
NCBI Gene ID3779
GeneCardsKCNK5
Human Protein AtlasKCNK5
Gene symbolKCNK5
ProteinTASK-2 / K2P5.1
Canonical UniProt entryO95279
Functional classTwo-pore-domain background potassium channel
Associated DiseasesMigraine
KG Connections18 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: inhibits
TP53 Gene
gene · KG edge: associated_with
TGFB3 Gene
gene · KG edge: associated_with
TGFB1 — Transforming Growth Factor Beta 1
gene · KG edge: associated_with
NR1D1 — Nuclear Receptor Subfamily 1 Group D Member 1 (
gene · KG edge: associated_with

Knowledge Graph (12 edges)

KCNK5 associated_with KCNK6
KCNK5 associated_with KCNK1
KCNK5 associated_with KCNK2
KCNK5 associated_with TGFB1
KCNK5 associated_with TP53
KCNK5 associated_with NR1D1
KCNK5 associated_with FXN
KCNK5 associated_with EPHA5
KCNK5 associated_with EP300
KCNK5 associated_with NLGN2