gene 735 words KG: NLGN2
Contents

NLGN2 Gene

🧬 Gene Info
Gene SymbolNLGN2
Full NameNeuroligin 2
Chromosome17p13.1
FunctionSynapse Formation: Mediates formation of GABAergic and glycinergic synapses through interaction with presynaptic neurexins.
Subcellular Localization**: Postsynaptic membranes, dendritic shafts
Molecular Weight156 kDa
Amino Acids411 aa
Exons19
UniProt IDQ9NZU5
NCBI Gene ID54587
Ensembl IDENSG00000144048
OMIM607629
GeneCardsNLGN2
Human Protein AtlasNLGN2
Associated DiseasesMigraine
InteractionsAND, ANXIETY, Bdnf, BDNF, CAT, COX4I1
KG Connections93 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.86
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.79
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: protects_against
Genes
index · KG edge: inhibits
BDNF Gene
gene · KG edge: inhibits
CAT — Catalase
gene · KG edge: inhibits
CDK4 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DISC1 inhibits NLGN2
ERBB4 inhibits NLGN2
GLUD1 inhibits NLGN2
NRG1 inhibits NLGN2
KCNK5 associated_with NLGN2
TGFB1 associated_with NLGN2
TP53 associated_with NLGN2
NR1D1 associated_with NLGN2
FXN associated_with NLGN2
EPHA5 associated_with NLGN2

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