gene 576 words KG: NETO2 2026-03-24
kind:genesection:genesstate:published
Contents

NETO2 — Neuropilin and Tolloid Like 2

🧬 Gene Info
Gene SymbolNETO2
Full NameNeuropilin And Tolloid Like 2
FunctionNETO2 (Neuropilin and Tolloid Like 2) is a transmembrane protein that plays important roles in synaptic function, neurodevelopment, and cell signaling.
Primary Expressionthe central nervous system and participates in the regulation of glutamate receptor trafficking and synaptic plasticity[@little2010]
UniProt IDQ9H6X4
Ensembl IDENSG00000167037
GeneCardsNETO2
Human Protein AtlasNETO2
Associated Diseasesneurodegeneration
InteractionsAKT1, MAPK1
KG Connections2 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.41
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.44

Related Analyses (3)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (15)

MAPK1 Gene
gene · KG edge: activates
AKT1 Gene
gene · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
ALS Therapeutic Landscape — Programs by Phase and Modal
disease · Pages share 3 hypotheses
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses

Knowledge Graph (2 edges)

AKT1 activates NETO2
MAPK1 activates NETO2