gene 1,217 words KG: P2RY14 2026-03-31
kind:genesection:genesstate:published
Contents

P2RY14 Gene - Purinergic Receptor P2Y14

🧬 Gene Info
Gene SymbolP2RY14
Full NamePurinergic Receptor P2Y14
AliasesPage for P2RY14 Gene
Chromosome3q25.1
Protein TypeReceptor
Functionencodes a G-protein coupled receptor that responds to UDP-sugars (particularly UDP-glucose, UDP-galactose, and UDP-N-acetylglucosamine) and mediates immune and inflammatory responses.
Primary Expressionimmune tissues and regulates:
Amino Acids336 aa
PathwaysPI3K
UniProt IDQ9HC97
NCBI Gene ID9939
GeneCardsP2RY14
Human Protein AtlasP2RY14
N-terminusExtracellular, glycosylation sites
Transmembrane domains7 α-helices crossing the membrane
Associated Diseasesneurodegeneration
KG Connections41 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (13)

Purinergic Signaling Polarization Control
Score: 0.55
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Multi-Modal Stress Response Harmonization
Score: 0.60
Microbial Inflammasome Priming Prevention
Score: 0.58

Related Analyses (10)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (11)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: expressed_in
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: therapeutic_target
P2RY1 Gene
gene · KG edge: expressed_in
P2RX7 Gene
gene · KG edge: expressed_in
P2RX4 Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

P2RY14 therapeutic_target P2RY1
P2RY14 therapeutic_target P2RX7
P2RY14 expressed_in MMP9
P2RY14 expressed_in FOS
P2RY14 expressed_in TAC1
P2RY14 expressed_in SPP1
P2RY14 expressed_in P2RY1
P2RY14 expressed_in P2RX1
P2RY14 expressed_in P2RX7
P2RY14 expressed_in P2RX4