| Gene Symbol | PIK3R3 |
| Full Name | Phosphoinositide-3-Kinase Regulatory Subunit 3 |
| Aliases | Phosphoinositide-3-Kinase Regulatory Subunit 3 (p55γ) |
| Chromosome | 1p36.22 |
| Function | encodes a protein with distinct structural features that differentiate it from other PI3K regulatory subunits. |
| Primary Expression | Brain (highest), immune cells, various tissues |
| Molecular Weight | ~55 kDa (hence "p55") |
| Amino Acids | 461 aa |
| Exons | 13 coding exons |
| Pathways | PI3K |
| UniProt ID | Q99836 |
| NCBI Gene ID | 5293 |
| Ensembl ID | ENSG00000117477 |
| OMIM | 606954 |
| GeneCards | PIK3R3 |
| Human Protein Atlas | PIK3R3 |
| Associated Diseases | neurodegeneration |
| Interactions | AKT, PI3K, ARC, CANCER, NESTIN, ALZHEIMER'S DISEASE |
| KG Connections | 52 knowledge graph edges |
| Databases | GeneCardsHPASTRING |