| Gene Symbol | PIK3CD |
| Aliases | PI3K catalytic subunit delta gene |
| Chromosome | 1p36.22 |
| Protein Type | Gene |
| Function | encodes a protein of 1,048 amino acids with a molecular weight of approximately 110 kDa. |
| Primary Expression | immune cells including T cells, B cells, natural killer cells, mast cells, and macrophages |
| Molecular Weight | 110 kDa |
| Amino Acids | 048 aa |
| Pathways | PI3K |
| GeneCards | PIK3CD |
| Human Protein Atlas | PIK3CD |
| p85-binding domain | Interacts with p85 regulatory subunits (PIK3R1, PIK3R2) that control enzyme activity and localization |
| C2 domain | Binds to cellular membranes through interactions with phospholipids |
| Helical domain | Involved in protein-protein interactions |
| Kinase domain | The catalytic center that phosphorylates PIP2 to generate PIP3 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Known Drugs/Compounds | dasatinib |
| Interactions | AKT, AKT1, AND, CANCER, GENES, INFLAMMATION |
| KG Connections | 64 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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