| Gene Symbol | POMC |
| Full Name | Proopiomelanocortin |
| Chromosome | 2p23.3 |
| Function | encodes a precursor protein that is cleaved to produce multiple biologically active peptides, including α-melanocyte stimulating hormone (α-MSH), β-endorphin, and adrenocorticotropic hormone (ACTH). |
| Primary Expression | the pituitary gland, hypothalamus, and skin melanocytes [@pomc] |
| Amino Acids | 267 aa |
| Exons | 3 |
| Pathways | Amyloid, Cholesterol, Cholesterol Metabolism, Er Stress, Immune Response |
| GeneCards | POMC |
| Human Protein Atlas | POMC |
| Peptide | Receptor |
| α-MSH | MC1R, MC3R, MC4R |
| β-Endorphin | μ-opioid receptor |
| ACTH | MC2R |
| γ-MSH | MC3R |
| Associated Diseases | ALS, Alopecia Areata, Alzheimer, Cancer, Hypertension, Ptsd |
| Interactions | JUN, STAT3, UCP2, LDLR, CRH, PRKAA1 |
| KG Connections | 188 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |