| Gene Symbol | ESR2 |
| Full Name | ESR2 — Estrogen Receptor Beta |
| Aliases | Estrogen Receptor Beta |
| Chromosome | 14q23.2 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | substantia nigra dopamine neurons
- Neuroprotection: ERβ agonists protect against MPTP-induced parkinsonism
- Clinical Relevance: Potential th |
| Pathways | PI3K, MAPK, Notch |
| UniProt ID | Q92731 |
| NCBI Gene ID | 2113 |
| Ensembl ID | ENSG00000140009 |
| GeneCards | ESR2 |
| Human Protein Atlas | ESR2 |
| Associated Diseases | ALS, Alzheimer, Cancer, Cardiovascular, Ischemia, Ms |
| Known Drugs/Compounds | rapamycin |
| Interactions | JUN, BCL2, Rb, GPX4, KL, CYTOKINES |
| KG Connections | 269 knowledge graph edges |
| Databases | GeneCardsHPASTRING |