| Gene Symbol | RASA1 |
| Full Name | RAS p120 GTPase Activating Protein |
| Chromosome | 5q14.1 |
| Protein Family | RAS GTPase-activating proteins |
| Function | is a critical regulator of RAS signaling pathways, functioning as a GTPase-activating protein (GAP) that accelerates the intrinsic GTP hydrolysis of RAS proteins. |
| Primary Expression | neurons and glial cells, particularly in the hippocampus and cortex
- Heart and skeletal muscle: Moderate expression
- Kidney and liver: Prese |
| Amino Acids | 1047 aa |
| Exons | 33 |
| Pathways | Cerebrovascular Development, MAPK signaling |
| UniProt ID | [P20156](https://www.uniprot.org/uniprot/P20156) |
| Ensembl ID | ENSG00000101577 |
| GeneCards | RASA1 |
| Human Protein Atlas | RASA1 |
| Vascular endothelium | High expression in endothelial cells lining blood vessels |
| Brain | Expressed in neurons and glial cells, particularly in the hippocampus and cortex |
| Associated Diseases | AD, ALI, ALS, AMI, Congenital Cerebrovascular Disease |
| Interactions | MAPK |
| KG Connections | 30 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |