gene 1,061 words KG: RILP 2026-03-21
kind:genesection:genesstate:published
Contents

RILP Gene

🧬 Gene Info
Gene SymbolRILP
Chromosome17p13.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight77 kDa
Amino Acids710 aa
Exons14
PathwaysNF-κB
Ensembl IDENSG00000131845
GeneCardsRILP
Human Protein AtlasRILP
N-terminal DomainContains the Rab7-binding region (RBD) that recognizes active GTP-bound Rab7
Central Coiled-Coil RegionMediates homodimerization and interaction with other proteins
C-terminal DomainContains the dynein-dynactin binding motif
Phosphorylation SitesMultiple serine/threonine residues regulated by kinases including LRRK2
Associated DiseasesAls
Known Drugs/Compoundsrapamycin
InteractionsRAB7, RAB7A, IGF2R, DYNACTIN, LDLR, SLC2A4
KG Connections95 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph