Contents

SPAST

🧬 Gene Info

Gene Symbol	SPAST
Protein Type	Enzyme
Function	Spastin is a microtubule-severing protein that plays essential roles in
Primary Expression	the nervous system:
GeneCards	SPAST
Human Protein Atlas	SPAST
Associated Diseases	Als, neurodegeneration, Spastic Paraplegia Type 4
Interactions	HDAC6, Ubiquitin
KG Connections	26 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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Knowledge Graph

SPAST associated_with COL4A1

SPAST associated_with SATB2

SPAST associated_with ATL1

SPAST associated_with PDHX

SPAST associated_with SLC16A2

SPAST associated_with GNAO1

COL4A1 associated_with SPAST

PDHX associated_with SPAST

GNAO1 associated_with SPAST

SATB2 associated_with SPAST