gene 1,663 words KG: SATB2
Contents

SATB2 - Special AT-Rich Sequence Binding Protein 2

🧬 Gene Info
Gene SymbolSATB2
Full NameSpecial AT-Rich Sequence Binding Protein 2
Chromosome2q33.3
Functionis a DNA-binding protein that functions as a master chromatin organizer and transcriptional regulator.
Molecular Weight87 kDa
Amino Acids757 aa
Exons11
PathwaysEpigenetic, Hedgehog, Notch, Tgf-Β, Wnt
UniProt IDQ9P2D8
NCBI Gene ID23305
Ensembl IDENSG00000119042
OMIM608161
GeneCardsSATB2
Human Protein AtlasSATB2
Associated DiseasesAls
InteractionsHDAC3, LCN2
KG Connections87 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (8)

Correcting Gut Microbial Dopamine Imbalance to Support Syste
Score: 0.61
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Extracellular Matrix Stiffness Modulation
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67

Related Analyses (7)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

GABA (Gamma-Aminobutyric Acid) - Neurodegenerative Dise
biomarker · KG edge: expressed_in
NeuRon Therapeutics
company · KG edge: expressed_in
Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
glutamate
general · KG edge: expressed_in
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: regulates

Knowledge Graph (12 edges)

TAZ associated_with SATB2
SATB2 regulates PIEZO1
SATB2 associated_with ATF4
SPAST associated_with SATB2
COL4A1 associated_with SATB2
SATB2 associated_with ATL1
SATB2 associated_with PDHX
SATB2 associated_with SLC16A2
SATB2 associated_with GNAO1
SATB2 expressed_in GAD1

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