gene 711 words KG: STAU2 2026-03-21
kind:genesection:genesstate:published
Contents

STAU2 Gene

🧬 Gene Info
Gene SymbolSTAU2
Full NameStaufen2
Chromosome8q13.3
FunctionThis transport is essential for local protein synthesis at synapses.
Primary Expressionneural progenitor cells and regulates genes involved in neuronal differentiation and migration
PathwaysMtor Signaling
UniProt IDQ9NUR2
NCBI Gene ID27067
Ensembl IDENSG00000100095
OMIM607010
GeneCardsSTAU2
Human Protein AtlasSTAU2
ApproachStatus
mRNA transport modulatorsResearch
Stress granule inhibitorsResearch
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ataxia, Dementia, Frontotemporal Dementia, Spinocerebellar Ataxia
Known Drugs/Compoundsrapamycin
InteractionsSTAUFEN2, MTOR, mTOR, RNA, STAU1
KG Connections77 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Phase-Separated Organelle Targeting
Score: 0.52
Stress Granule Phase Separation Modulators
Score: 0.49
RNA Granule Nucleation Site Modulation
Score: 0.48
Cryptic Exon Silencing Restoration
Score: 0.46

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Packard Center for ALS Research
institution · KG edge: associated_with
Dementia Australia
institution · KG edge: associated_with
MTOR Gene
gene · KG edge: activates
C9orf72 — Chromosome 9 Open Reading Frame 72
gene · KG edge: therapeutic_target
c9orf72-als-ftd-phenotype-mechanism
general · KG edge: associated_with

Knowledge Graph (12 edges)

STAU2 therapeutic_target MTOR
STAU2 therapeutic_target C9ORF72
STAU2 activates Stress Granule Formation
STAU2 associated_with Spinocerebellar Ataxia Type 2
STAU2 regulates Mrna Trafficking
STAU2 activates MTOR
STAU2 involved_in Mtor Signaling
STAU2 expressed_in neurodegeneration
STAU2 expressed_in cerebellum
STAU2 induces_formation stress granules