gene 968 words KG: STXBP2 2026-03-21
kind:genesection:genesstate:published
Contents

STXBP2 — Syntaxin Binding Protein 2

🧬 Gene Info
Gene SymbolSTXBP2
Full NameSyntaxin Binding Protein 2 (Munc18-2)
AliasesMunc18-2
Chromosome19p13.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionimmune cells:
Molecular Weight66 kDa
Amino Acids593 aa
UniProt IDO00139
NCBI Gene ID9504
Ensembl IDENSG00000178726
OMIM601717
GeneCardsSTXBP2
Human Protein AtlasSTXBP2
Protein Length593 amino acids
Associated DiseasesHemophagocytic Lymphohistiocytosis, Microvillus Inclusion Disease
KG Connections29 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.41
Synaptic Vesicle Tau Capture Inhibition
Score: 0.34

Related Analyses (6)

Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (15)

p38 MAPK Protein
protein · KG edge: biomarker_for
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: biomarker_for
Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: biomarker_for
Packard Center for ALS Research
institution · KG edge: biomarker_for
TRAF6 Gene
gene · KG edge: biomarker_for

Knowledge Graph (12 edges)

STXBP2 biomarker_for FLNA
STXBP2 biomarker_for CTSD
STXBP2 biomarker_for JUNB
STXBP2 biomarker_for NFKBIA
STXBP2 biomarker_for TRAF6
STXBP2 biomarker_for EGR2
STXBP2 biomarker_for SPI1
STXBP2 biomarker_for P38
STXBP2 associated_with Hemophagocytic Lymphohistiocytosis
STXBP2 associated_with Microvillus Inclusion Disease