| Gene Symbol | FLNA |
| Full Name | Filamin A |
| Chromosome | Xq28 |
| Function | FLNA (Filamin A) is a 280 kDa actin-binding protein that serves as a critical scaffold for protein-protein interactions in eukaryotic cells[@stossel2001] |
| Molecular Weight | 280 kDa |
| Pathways | Leading Edge Extension |
| UniProt ID | [P21333](https://www.uniprot.org/uniprot/P21333) |
| Ensembl ID | ENSG00000196924 |
| OMIM | 300017 |
| GeneCards | FLNA |
| Human Protein Atlas | FLNA |
| N-terminal actin-binding domain | Binds to F-actin |
| 24 repeat repeats | Each containing two calponin homology (CH) domains that serve as protein interaction surfaces |
| C-terminal dimerization domain | Enables orthogonal network formation |
| Associated Diseases | Heterotopic Neurons |
| Interactions | G3BP1, OPTN, RNA |
| KG Connections | 35 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!