gene 1,067 words KG: TERC
Contents

TERC Gene

🧬 Gene Info
Gene SymbolTERC
Full NameTelomerase RNA Component
Chromosome3q26.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids~451 nucleotides
PathwaysTelomere Dysfunction
NCBI Gene ID7012
Ensembl IDENSG00000264364
OMIM602322
GeneCardsTERC
Human Protein AtlasTERC
Associated DiseasesAls, Inflammation, Ms, Senescence
InteractionsIL-6, IL-8, MICRORNAS
KG Connections60 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (76)

Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65
APOE-Mediated Synaptic Lipid Raft Stabilization
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Multi-Modal CRISPR Platform for Simultaneous Editing and Mon
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
Restoring Neuroprotective Tryptophan Metabolism via Targeted
Score: 0.61
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.61
The Glial Ketone Metabolic Shunt Hypothesis
Score: 0.61
Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Ci
Score: 0.60
Netrin-1 Gradient Restoration
Score: 0.59
VCP-Mediated Autophagy Enhancement
Score: 0.59
Extracellular Vesicle Biogenesis Modulation
Score: 0.58
← Prevpg 3/4Next →

Related Analyses (28)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (4)

Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: contributes_to
Genes
index · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: contributes_to

Knowledge Graph (12 edges)

TERT associated_with TERC
TERT expressed_in TERC
TERC involved_in Telomere Dysfunction
TERC regulates Telomere Dysfunction
TERC involved_in Telomere Maintenance
TERT encodes TERC
TERC causes Telomere Dysfunction
TERC regulates Senescence
TERC associated_with Als
TERC regulates Ms

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.