gene 1,067 words KG: TERC
Contents

TERC Gene

🧬 Gene Info
Gene SymbolTERC
Full NameTelomerase RNA Component
Chromosome3q26.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids~451 nucleotides
PathwaysTelomere Dysfunction
NCBI Gene ID7012
Ensembl IDENSG00000264364
OMIM602322
GeneCardsTERC
Human Protein AtlasTERC
Associated DiseasesAls, Inflammation, Ms, Senescence
InteractionsIL-6, IL-8, MICRORNAS
KG Connections60 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (76)

HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.57
Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy
Score: 0.55
HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor
Score: 0.54
Lysosomal Membrane Repair Enhancement
Score: 0.54
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
PINK1/Parkin-Independent Mitophagy Bypass for Enhanced Donor
Score: 0.53
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Synthetic Biology Approach: Designer Mitochondrial Export Sy
Score: 0.51
Microglia-Derived Extracellular Vesicle Engineering for Targ
Score: 0.48
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
Optogenetic Control of Mitochondrial Transfer Networks
Score: 0.48
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43
Gap Junction Hemichannel Modulation for Controlled Mitochond
Score: 0.36
← Prevpg 4/4

Related Analyses (28)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (4)

Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: contributes_to
Genes
index · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: contributes_to

Knowledge Graph (12 edges)

TERT associated_with TERC
TERT expressed_in TERC
TERC involved_in Telomere Dysfunction
TERC regulates Telomere Dysfunction
TERC involved_in Telomere Maintenance
TERT encodes TERC
TERC causes Telomere Dysfunction
TERC regulates Senescence
TERC associated_with Als
TERC regulates Ms

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