gene 923 words KG: TLR6
Contents

TLR6 Gene

🧬 Gene Info
Gene SymbolTLR6
Full NameToll-Like Receptor 6
Chromosome4p14
Protein TypeReceptor
FunctionTLR6 typically forms heterodimers with TLR2 to recognize a broad range of ligands:
Primary Expressionvarious cell types with highest expression in immune cells:
Molecular Weight91 kDa
Amino Acids200 aa
PathwaysLysosomal Degradation
UniProt IDQ9NYK5
NCBI Gene ID10333
Ensembl IDENSG00000174128
OMIM607209
GeneCardsTLR6
Human Protein AtlasTLR6
Associated Diseasesneurodegeneration
InteractionsALZHEIMER'S DISEASE, AQP4, ASTROCYTES, GFAP, GJA1, IL1B
KG Connections11 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.86
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.79
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.76
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75

Related Analyses (7)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (12)

Astrocytes
cell · KG edge: activates
Microglia
cell · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
Astrocytes
entity · KG edge: activates
GFAP (Redirect)
redirect · KG edge: activates

Knowledge Graph (11 edges)

AQP4 activates TLR6
TLR6 activates GFAP
TLR6 activates IL1B
TLR6 activates TNF
TLR6 activates VIM
TLR6 activates GJA1
TLR6 activates MICROGLIA
TLR6 activates ALZHEIMER'S DISEASE
TLR6 activates ASTROCYTES
TLR6 activates Alzheimer

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