gene 1,152 words KG: VIM 2026-03-24
kind:genesection:genesstate:published
Contents

VIM Gene

🧬 Gene Info
Gene SymbolVIM
Full NameVimentin
Chromosome10p13
Functionencodes a type III intermediate filament protein that is one of the most widely expressed structural proteins in eukaryotic cells.
Molecular Weight57 kDa
Amino Acids466 aa
Exons9
PathwaysAutophagy, Immune Response, Mapk, Notch Signaling, Proteasome
Ensembl IDENSG00000026025
OMIM193060
GeneCardsVIM
Human Protein AtlasVIM
Associated DiseasesDiabetes, Inflammation, Parkinson, Parkinson's disease
Known Drugs/CompoundsColumbianadin, rapamycin
InteractionsBDNF, FGF23, FNDC5, GJA1, VIMENTIN, FGF21
KG Connections379 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (13)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52

Related Analyses (6)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: biomarker_for
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: biomarker_for
Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: expressed_in
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: biomarker_for

Knowledge Graph (12 edges)

VIM regulates BECN1
VIM associated_with HDAC6
VIM regulates GAPDH
VIM associated_with MAP1LC3B
VIM associated_with MAP3K5
VIM associated_with UVRAG
VIM regulates H2AX
VIM associated_with OCLN
VIM associated_with RAC1
VIM associated_with PIK3C3