gene 1,801 words KG: UNG
Contents

UNG Gene

🧬 Gene Info
Gene SymbolUNG
AliasesUracil-DNA Glycosylase
Chromosome12q24.31
Protein TypeEnzyme
Functionis a critical DNA repair enzyme that protects the genome from uracil incorporation and deamination.
Molecular Weight36 kDa
Amino Acids313 aa
Exons7
PathwaysNeurogenesis
Ensembl IDENSG00000166200
GeneCardsUNG
Human Protein AtlasUNG
Associated Diseasesneurodegeneration
InteractionsDEMENTIA, DEPRESSION, NEURODEGENERATION, STROKE
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
PARP1 Inhibition Therapy
Score: 0.74
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Neurodegeneration
disease · KG edge: implicated_in
DNA Methylation
entity · KG edge: associated_with
Neurogenesis
entity · KG edge: activates
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: regulates
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: associated_with

Knowledge Graph (12 edges)

STX17 associated_with UNG
ATP5MC1 associated_with UNG
TXNRD1 associated_with UNG
MFN2 associated_with UNG
UNG associated_with SDHB
MITOCHONDRIAL DYSFUNCTION associated_with UNG
UNG associated_with Dna Methylation
UNG associated_with Complement
NEURODEGENERATION activates UNG
UNG activates STROKE

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