gene 561 words KG: SDHB 2026-03-21
kind:genesection:genesstate:published
Contents

SDHB Gene

🧬 Gene Info
Gene SymbolSDHB
FunctionThe SDHB gene encodes SDHB Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysDna Methylation, Complement
Ensembl IDENSG00000117118
GeneCardsSDHB
Human Protein AtlasSDHB
Associated DiseasesALS, Kidney Cancer
InteractionsPPARG, PARK7, BACE1, AMPK, ACETYL-COA, SIRT3
KG Connections41 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
Circadian Clock-Autophagy Synchronization
Score: 0.55
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.53

Related Analyses (11)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

See Also (15)

huntington-disease-treatment
therapeutic · KG edge: interacts_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: interacts_with
Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: interacts_with
TXNRD1 — Thioredoxin Reductase 1
gene · KG edge: regulates

Knowledge Graph (12 edges)

SDHB interacts_with PPARG
SDHB interacts_with PARK7
SDHB interacts_with BACE1
SDHB causes Kidney Cancer
SDHB participates_in ferroptosis
SDHB associated_with Dna Methylation
SDHB associated_with Complement
SDHB interacts_with AMPK
SDHB interacts_with ACETYL-COA
SDHB interacts_with Alzheimer