gene 871 words KG: GFRAL
Contents

GFRAL Gene - GDNF Receptor Alpha Like

🧬 Gene Info
Gene SymbolGFRAL
Full NameGDNF Receptor Alpha Like
AliasesPage for GFRAL Gene, Page for GFRAL Protein
Chromosome6p12.1
Protein TypeReceptor
Functionis a cell surface receptor that belongs to the GDNF receptor family (GFRα).
Primary Expressionspecific neuronal populations: - Substantia nigra pars compacta: Dopaminergic neurons - Ventral tegmental area: Mesolimbic dopamine neurons -
Molecular Weight50 kDa
PathwaysPI3K
UniProt IDQ6UXB5
NCBI Gene ID390538
Ensembl IDENSG00000173137
OMIM615866
GeneCardsGFRAL
Human Protein AtlasGFRAL
Associated DiseasesALS
InteractionsADCY3, AND, CANCER, CYTOKINES, GDF15, Gdnf
KG Connections79 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

GDF15-GFRAL Axis as Systemic Autophagy-Senescence Integrator
Score: 0.66

Knowledge Graph (12 edges)

GLP1R inhibits GFRAL
GFRAL inhibits GDNF
GDNF inhibits GFRAL
GFRAL contributes_to BDNF
GFRAL inhibits GLP1R
HDAC6 activates GFRAL
GDNF regulates GFRAL
SHH activates GFRAL
GFRAL activates ADCY3
GFRAL expressed_in Brainstem

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.