SciDEX — GDF15

Target	Relation	Type	Str
Frailty	biomarker_for	phenotype	0.95
Body Weight	downregulates	phenotype	0.90
Dementia Risk	risk_factor_for	phenotype	0.85
BDNF	activates	protein	0.85
body weight	associated_with	phenotype	0.85
hepatocellular carcinoma	causes	disease	0.80
BDNF NEURONS	activates	cell_type	0.80
neurodegeneration	contributes_to	process	0.75
neuroprotection	mediates	process	0.75
oxidative stress response	participates_in	pathway	0.70
GDNF	expressed_in	gene	0.60
GFRAL	expressed_in	gene	0.60
GLP1R	expressed_in	gene	0.60
KL	activates	gene	0.60
PLAU	activates	gene	0.60
VIM	activates	gene	0.60
cancer	implicated_in	disease	0.60
cardiovascular disease	implicated_in	disease	0.60
cancer	regulates	disease	0.60
GDNF	associated_with	gene	0.60
GFRAL	associated_with	gene	0.60
GFRAL	interacts_with	gene	0.60
MMP1	interacts_with	gene	0.60
TFEB	causes	gene	0.60
TFEB	inhibits	gene	0.60
TFEB	associated_with	gene	0.60
GDNF	interacts_with	gene	0.60
PGRN	activates	gene	0.60
TGF	implicated_in	gene	0.60
TGF-beta signaling	participates_in	pathway	0.60
diabetes	associated_with	disease	0.60
multiple sclerosis	activates	disease	0.60
diabetes	activates	disease	0.60
senescence	participates_in	pathway	0.60
macrophages	expressed_in	cell_type	0.60
endothelial cells	expressed_in	cell_type	0.60
blood-brain barrier	participates_in	pathway	0.60
TGF	associated_with	gene	0.60
T cells	expressed_in	cell_type	0.60
neurons	expressed_in	cell_type	0.55

Source	Relation	Type	Str
hepatic stellate cells	produces	cell_type	0.90
Metformin	upregulates	drug	0.85
autophagy	regulates	phenotype	0.80
BMPR1A	interacts_with	gene	0.80
BDNF	associated_with	gene	0.60
BDNF	activates	gene	0.60
CX3CL1	activates	gene	0.60
CXCL10	activates	gene	0.60
FGF21	activates	gene	0.60
FGF23	activates	gene	0.60
FNDC5	activates	gene	0.60
BACE1	activates	gene	0.60
BACE1	associated_with	gene	0.60
FGF21	expressed_in	gene	0.60
AMPK	activates	gene	0.60
metformin	targets	drug	0.60

GDF15