gene 842 words KG: IL33
Contents

IL33 Gene

🧬 Gene Info
Gene SymbolIL33
Full NameInterleukin-33
Chromosome9p24.1
FunctionIL33 is a cytokine with alarmin function:
Molecular Weight30 kDa
PathwaysMAPK pathway
UniProt IDQ9BY84
NCBI Gene ID90865
Ensembl IDENSG00000144233
OMIM608678
GeneCardsIL33
Human Protein AtlasIL33
N-terminal domainChromatin-binding domain
C-terminal domainCytokine receptor-binding domain
Full-length formBiologically active as nuclear protein
Associated DiseasesALS
InteractionsADRA1A, ADRA2A, ADRB1, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID
KG Connections81 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

IL33 activates ZBP1
IL33 inhibits MLKL
IL33 inhibits RIPK3
IL1RL1 activates IL33
AKT implicated_in IL33
IL33 expressed_in EGFR
IL33 activates dural Tregs
IL33 therapeutic_target CD33
CD33 activates IL33
CD33 therapeutic_target IL33

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