gene 1,735 words KG: MBD1
Contents

MBD1 — Methyl-CpG Binding Domain Protein 1

🧬 Gene Info
Gene SymbolMBD1
Full NameMethyl-CpG Binding Domain Protein 1
Chromosome18q21.1
Protein FamilyMBD (Methyl-CpG Binding Domain)
Functionis a critical epigenetic regulator that binds to methylated CpG dinucleotides in DNA and recruits chromatin remodeling complexes to silence gene expression.
Molecular Weight66 kDa
Amino Acids605 aa
Exons17
PathwaysDna Methylation, epigenetic regulation
UniProt IDQ9P273
NCBI Gene ID4153
Ensembl IDENSG00000141644
OMIM156311
GeneCardsMBD1
Human Protein AtlasMBD1
Associated Diseasesneurodegeneration
InteractionsC-FOS, EZH2, FOS, SDHB, VHL
KG Connections10 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (10 edges)

VHL activates MBD1
MBD1 activates FOS
MBD1 activates SDHB
MBD1 associated_with TREM2
EZH2 interacts_with MBD1
MBD1 activates C-FOS
MBD1 activates Als
MBD1 activates Dna Methylation
MBD1 binds TREK-1
MBD1 participates_in epigenetic regulation

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.