| Name | Calcium Dysregulation in 4R-Tauopathies — Cross-Disease Comparison |
| Category | evidence:strong |
| Summary | Comprehensive comparison of calcium dysregulation mechanisms across PSP, CBD, AGD, GGT, and FTDP-17: VGCC alterations, mitochondrial calcium handling, ER stress, and therapeutic targets |
| Key Genes/Proteins | MCU, Trpml1, calcium_channels, amyloid_beta, alpha_synuclein, huntingtin |
| Related Diseases | actin filament stability, synaptic_transmission, synaptic_plasticity, aging, neurodegeneration |
| Related Pathways | cellular repair pathways |
| Linked Hypotheses | 6 hypotheses |