gene 1,111 words KG: P2RY13
Contents

P2RY13

🧬 Gene Info
Gene SymbolP2RY13
AliasesPurinergic Receptor P2Y13
Chromosome3q25.2
Protein TypeReceptor
Functionis a G protein-coupled receptor (GPCR) belonging to the P2Y receptor family that responds to extracellular nucleotides, particularly ATP and ADP.
Primary Expressionimmune cells, including microglia in the brain, where it plays a crucial role in modulating inflammatory re
Molecular Weight42 kDa
Amino Acids339 aa
PathwaysPI3K, MAPK pathway, NF-κB
Ensembl IDENSG00000144647
GeneCardsP2RY13
Human Protein AtlasP2RY13
Associated DiseasesAtherosclerosis, Cardiovascular, Ms
InteractionsCSF1R, CX3CR1, P2RY12, TMEM119
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

P2RY12/P2RY13 Purinergic Receptor Metabolic Rewiring
Score: 0.49

Knowledge Graph (12 edges)

MMP9 biomarker_for P2RY13
GRM1 regulates P2RY13
CCR8 regulates P2RY13
P2RY13 regulates ADCY2
CSF1R inhibits P2RY13
CX3CR1 inhibits P2RY13
P2RY12 inhibits P2RY13
P2RY13 inhibits TMEM119
IMMUNE INFILTRATION associated_with P2RY13
INFLAMMATION contributes_to P2RY13

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