| Gene Symbol | ADCY2 |
| Full Name | Adenylate Cyclase 2 |
| Chromosome | 5p15.2 |
| Protein Type | Enzyme |
| Function | is a membrane-bound enzyme that catalyzes the conversion of ATP to cyclic adenosine monophosphate (cAMP), a crucial second messenger in cellular signaling. |
| Subcellular Localization | ADCY2 is localized to: |
| Molecular Weight | 125 kDa |
| UniProt ID | [Q08462](https://www.uniprot.org/uniprot/Q08462) |
| Ensembl ID | ENSG00000045081 |
| OMIM | 103070 |
| GeneCards | ADCY2 |
| Human Protein Atlas | ADCY2 |
| N-terminal regulatory domain | Contains calmodulin-binding sites for calcium regulation |
| Membrane-spanning helices | 12 transmembrane domains organized in 6 pairs (M1-M6) |
| Cytoplasmic catalytic domains | Two large cytoplasmic loops (C1 and C2) form the active site |
| Associated Diseases | Alzheimer's disease (AD |
| Interactions | C3AR1, CCR5, CNR2, CXCL12, CXCL8, GRM2 |
| KG Connections | 40 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |