gene 1,222 words KG: PDE4C
Contents

PDE4C — Phosphodiesterase 4C

🧬 Gene Info
Gene SymbolPDE4C
Full NamePhosphodiesterase 4C
Chromosome19q13.12
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight68 kDa
PathwaysApoptosis, Complement, Exocytosis, Mitochondrial Function
UniProt ID[Q08431](https://www.uniprot.org/uniprot/Q08431)
Ensembl IDENSG00000074527
OMIM610172
GeneCardsPDE4C
Human Protein AtlasPDE4C
LungHighest expression in airway smooth muscle and epithelial cells
BrainModerate expression in cortex, hippocampus, and cerebellum
TestisHigh expression in spermatogenic cells
Immune cellsPresent in mast cells and eosinophils
Associated Diseasesneurodegeneration
InteractionsNGF, SLC24A2
KG Connections29 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

NBN regulates PDE4C
SGK3 regulates PDE4C
TNF regulates PDE4C
SLC24A2 activates PDE4C
DNAJC2 regulates PDE4C
CHMP3 regulates PDE4C
PDE4C regulates BAG1
PDE4C regulates VTI1B
PDE4C regulates EIF4G1
PDE4C regulates NOX1

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