gene

SLC24A2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC24A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections
0Hypotheses
0Analyses
25Outgoing
8Incoming

Summary

Page for SLC24A2 — Solute Carrier Family 2 Member 4A2 (SLC24A2)

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🧬 Gene Info
Gene SymbolSLC24A2
Full NameSolute Carrier Family 24 Member 2 (Na+/Ca2+ Exchanger 2)
Chromosome9p21
Functionis a hallmark of many neurodegenerative diseases.
Primary Expressionthe olfactory bulb, where it plays a critical role in olfactory receptor neuron function
PathwaysApoptosis, Complement, Exocytosis, Mitochondrial Function
UniProt IDO43295
NCBI Gene ID8994
Ensembl IDENSG00000159339
OMIM609521
GeneCardsSLC24A2
Human Protein AtlasSLC24A2
Associated Diseasesneurodegeneration
InteractionsPDE4C, NGF
KG Connections33 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: SLC24A2 — AlphaFold O43295 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

SLC24A2 — Solute Carrier Family 2 Member 4A2 (SLC24A2)

gene · 793 words

vti1b

gene · 1294 words

Genes

index · 271 words

Pathway Diagram

graph TD
    SLC24A2["<b>SLC24A2</b>"]
    Dementia{"Dementia"}
    SLC24A2 -->|"regulates"| Dementia
    Schizophrenia{"Schizophrenia"}
    SLC24A2 -->|"regulates"| Schizophrenia
    Alzheimer{"Alzheimer"}
    SLC24A2 -->|"regulates"| Alzheimer
    Multiple_Sclerosis{"Multiple Sclerosis"}
    SLC24A2 -->|"regulates"| Multiple_Sclerosis
    Als{"Als"}
    SLC24A2 -->|"regulates"| Als
    Cancer{"Cancer"}
    SLC24A2 -->|"regulates"| Cancer
    Ms{"Ms"}
    SLC24A2 -->|"regulates"| Ms
    APOPTOSIS["APOPTOSIS"]
    SLC24A2 -->|"regulates"| APOPTOSIS
    DNAJC2["DNAJC2"]
    SLC24A2 -->|"regulates"| DNAJC2
    CHMP3["CHMP3"]
    SLC24A2 -->|"regulates"| CHMP3
    PDE4C["PDE4C"]
    SLC24A2 -->|"activates"| PDE4C
    BAG1["BAG1"]
    SLC24A2 -->|"regulates"| BAG1
    NBN["NBN"]
    NBN -->|"regulates"| SLC24A2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"regulates"| SLC24A2
    SGK3["SGK3"]
    SGK3 -->|"regulates"| SLC24A2
    TNF["TNF"]
    TNF -->|"regulates"| SLC24A2
    CANCER["CANCER"]
    CANCER -->|"regulates"| SLC24A2
    style SLC24A2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (25)

TargetRelationTypeStr
Dementiaregulatesdisease0.65
Schizophreniaregulatesdisease0.65
Alzheimerregulatesdisease0.65
Multiple Sclerosisregulatesdisease0.65
Alsregulatesdisease0.65

Incoming (8)

SourceRelationTypeStr
NBNregulatesgene0.60
SGK3regulatesgene0.60
TNFregulatesgene0.60
EFNB3implicated_ingene0.60
EPHB6implicated_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found