protein 879 words KG: ALSIN 2026-03-29
kind:proteinsection:proteinsstate:published
Contents

Alsin Protein (ALS2)

🔬 Protein Info
Gene SymbolALSIN
Full NameAlsin (ALSIN)
AliasesALS2/Alsin
Chromosome2q33.
Protein TypeGene
FunctionAlsin is a multiunctional protein with several key cellular roles:
Subcellular Localization</strong></td><td>Endosomes, Cytoplasm</td></tr>
Molecular Weight210 kDa
Amino Acids847 aa
GeneCardsALSIN
Human Protein AtlasALSIN
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Glaucoma
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Cryptic Exon Silencing Restoration
Score: 0.46
Cross-Seeding Prevention Strategy
Score: 0.45
Glycine-Rich Domain Competitive Inhibition
Score: 0.43

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (22)

s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40
Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40
ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40
Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40

See Also (15)

Packard Center for ALS Research
institution · KG edge: associated_with
TARDBP — TAR DNA Binding Protein 43
gene · KG edge: associated_with
FIG4 — FIG4 Phosphatase Homolog
gene · KG edge: associated_with
ALS9 - Amyotrophic Lateral Sclerosis 9
gene · KG edge: associated_with
ALS8 - Amyotrophic Lateral Sclerosis 8
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ALSIN associated_with ALS4
ALSIN associated_with ALS9
ALSIN associated_with TARDBP
ALSIN associated_with ALS7
ALSIN associated_with ALS10
ALSIN associated_with SOD1
ALSIN associated_with ALS
ALSIN associated_with GENES
ALSIN associated_with MOTOR NEURONS
ALSIN associated_with DNA