protein 1,714 words KG: AXLPROTEIN 2026-03-31
kind:proteinsection:proteinsstate:published
Contents

Axl Protein

🔬 Protein Info
Gene SymbolAXLPROTEIN
Protein FamilyTAM Receptor Tyrosine Kinase Family
Protein TypeReceptor
Functionis a member of the TAM (TYRO3, AXL, MERTK) receptor tyrosine kinase family that plays versatile roles in both normal physiology and disease pathogenesis.
Primary Expressionneurons, microglia, astrocytes, and vascular endothelial cells
Subcellular LocalizationCell membrane, Endosomes, Nucleus
Molecular Weight140 kDa (full-length)
UniProt IDQ9U6C5
GeneCardsAXLPROTEIN
Human Protein AtlasAXLPROTEIN
Protein NameAXL (AXL Receptor Tyrosine Kinase)
GeneAXL
PDB ID5WUR, 6JNK, 7MBX
Associated DiseasesAging, Alzheimer, Cancer, INFLAMMATION, Ms, NEUROINFLAMMATION
InteractionsCHIT1, CXCL10, MMP12, CXCL1, EZH2, BRAF
KG Connections201 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph