| Gene Symbol | BRCA1 |
| Full Name | BRCA1 DNA Repair Associated |
| Chromosome | 17q21 |
| Function | BRCA1 is a key component of the DNA damage response machinery |
| Primary Expression | most tissues with high expression in:
- Breast and ovarian epithelium
- Testis
- Brain (neurons and glia)
- Proliferating cells |
| Pathways | Apoptosis, Autophagy, Cell Cycle, Dna Repair, Immune Response |
| UniProt ID | P38398 |
| NCBI Gene ID | 672 |
| Ensembl ID | ENSG00000012048 |
| OMIM | 113705 |
| GeneCards | BRCA1 |
| Human Protein Atlas | BRCA1 |
| BRCA2 (FANCD1) | Homologous recombination |
| PALB2 | DNA damage response |
| RAD51 | Strand invasion |
| Associated Diseases | ALS, Breast Cancer, Cancer, Carcinoma, Melanoma |
| Interactions | RB1CC1, MTOR, GPX4, RAD51, SLC7A11, HNRNPH1 |
| KG Connections | 462 knowledge graph edges |
| Databases | GeneCardsHPASTRING |