protein 615 words KG: CPLX2PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Complexin-2 Protein

🔬 Protein Info
Gene SymbolCPLX2PROTEIN
Full NameComplexin-2
Protein FamilyComplexin family (CPLX1-4)
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular LocalizationCytosolic (presynaptic terminal)
Molecular Weight14.5 kDa
UniProt IDO75178
GeneCardsCPLX2PROTEIN
Human Protein AtlasCPLX2PROTEIN
Protein NameComplexin-2
GeneCPLX2
PDB ID1GID, 2N0P
ApproachTarget
Small molecule modulatorsCPLX2-SNARE interaction
Gene therapyAAV-CPLX2 for neuroprotection
Associated DiseasesAlzheimer, neurodegeneration
InteractionsDNM1L, ICAM1, PINK1, TFAM, TNF, BDNF
KG Connections15 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph