protein 1,190 words KG: DATPROTEIN 2026-03-13
kind:proteinsection:proteinsstate:published
Contents

DAT Protein

🔬 Protein Info
Gene SymbolDAT
AliasesDATPROTEIN
Protein FamilyNa+/Cl- dependent neurotransmitter transporter (SLC6)
FunctionDat Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular LocalizationPlasma membrane, presynaptic terminals
Molecular Weight~79 kDa (glycosylated)
Pathwaysdopamine neurotransmission, membrane diffusion, vesicular traffic
UniProt IDQ01959
GeneCardsDAT
Human Protein AtlasDAT
Protein NameDopamine Transporter (DAT)
GeneSLC6A3
PDB4MDS, 5JU6
Associated DiseasesALS, Alzheimer's disease, Levodopa-Induced Motor Complications, Parkinson, Parkinson's disease
Known Drugs/Compoundslevodopa, curcumin
InteractionsLRRK2, GBA1, GBA, AND, EN1, EN2
KG Connections69 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph