| Gene Symbol | EGR1 |
| Full Name | Early Growth Response 1 |
| Aliases | Early Growth Response protein 1 |
| Chromosome | 5q31 |
| Protein Family | C2H2-type zinc finger transcription factor |
| Protein Type | Transcription Factor |
| Function | EGR1 is an immediate-early transcription factor that regulates neuronal plasticity, learning, memory, and response to neural activity. |
| Primary Expression | Brain (hippocampus, cortex, basal ganglia), peripheral nervous system |
| Subcellular Localization | Nucleus |
| Molecular Weight | ~59.8 kDa |
| Amino Acids | 543 |
| Pathways | MAPK |
| UniProt ID | P18146 |
| NCBI Gene ID | 1958 |
| Ensembl ID | ENSG00000120738 |
| OMIM | 129500 |
| GeneCards | EGR1 |
| Human Protein Atlas | EGR1 |
| Associated Diseases | AD, ALI, ALS, ARM, Alzheimer |
| Known Drugs/Compounds | metformin |
| Interactions | HNRNPK, NDP52, HNRNPA1, IGF1, FGF2, IGF1R |
| KG Connections | 421 knowledge graph edges |
| Databases | GeneCardsHPASTRING |